NOCISCAN Suite helps identify degeneration and pain between discs in the lumbar spine. Our software harnesses the power of MR Spectroscopy (MRS) to aid physicians in making more informed decisions about a patient’s treatment path, including information that helps physicians determine which specific discs require treatment.

Enhancing the Value of
Lumbar MR Exams

NOCISCAN Suite, through non-invasive means, gives radiologists and physicians the power to compare the differences in degenerative pain biomarkers between lumbar discs in patients receiving MRS exams.

Helps enable physicians to identify degeneration and pain between discs in the lumbar spine to determine the optimal treatment path.

How it Works

Disk Voxelation via the MRI Images

A three-dimensional volume is defined by a ‘box’ drawn by the MR operator/technician in the disc nucleus of the MRI images. This is then “vibrated” by the MR scanner using a NOCISCAN-LS exam protocol using existing MRS pulse sequences, but optimized for the specific application to discs.

Spectral Analysis (Cloud)

The acquired data is uploaded to a secure cloud-based post-processor for analysis. Signals acquired from the nucleus are processed by NOCICALC-LS™ to calculate ratios of the spectral values for certain combinations of the chemicals as degenerative pain markers. Outputs of NOCICALC-LS are used by NOCIGRAM-LS™. This includes making analytical calculations to generate a “NOCISCORE” that is correlated, per a clinical trial, to the results of another invasive reference discography test for pain.

Report Review

A NOCICALC-LS and/or NOCIGRAM-LS Report is then returned from the cloud post-processor back into the patient’s records in the originating PACS network and onto the NociWeb user interface. The NOCICALC-LS report provides the data to help evaluate chemical composition of a disc, relative to other discs. The NOCIGRAM-LS report provides an intuitive format to show the relative degenerative painful chemical comparisons between discs to assist a doctor, in combination with other available patient data, in diagnosing disc conditions, such as discogenic pain and/or degenerative disc disease.


Success rate for surgical patients with treatment at NOCI+ Discs**

**Source: European Spine Journal - January 2019 (pg. 12)

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