Say Hello to
NOCISCAN™ Suite

A revolutionary software suite that works with existing high field MR systems and MRS pulse sequence packages using an optimized protocol to conduct MRS exams of lumbar discs.

Say Hello to
NOCISCAN™ Suite

A revolutionary software suite that works with existing high field MR systems and MRS pulse sequence packages using an optimized protocol to conduct MRS exams of lumbar discs.

How it Works

It starts with an MR Spectroscopy scan. Then, using our software, each disc is evaluated for spectral signatures for pain biomarkers derived from degenerative pain biomarkers.

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Disk Voxelation via the MRI Images

A three-dimensional volume is defined by a ‘box’ drawn by the MR operator/technician in the disc nucleus of the MRI images. This is then “vibrated” by the MR scanner using a NOCISCAN-LS exam protocol using existing MRS pulse sequences, but optimized for the specific application to discs.

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Spectral Analysis (Cloud)

The acquired data is uploaded to a secure cloud-based post-processor for analysis. Signals acquired from the nucleus are processed by NOCICALC-LS™ to calculate ratios of the spectral values for certain combinations of the chemicals as degenerative pain markers. Outputs of NOCICALC-LS are used by NOCIGRAM-LS™. This includes making analytical calculations to generate a “NOCISCORE” that is correlated, per a clinical trial, to the results of another invasive reference discography test for pain.

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Report Review

A NOCICALC-LS and/or NOCIGRAM-LS Report is then returned from the cloud post-processor back into the patient’s records in the originating PACS network and onto the NociWeb user interface. The NOCICALC-LS report provides the data to help evaluate chemical composition of a disc, relative to other discs. The NOCIGRAM-LS report provides an intuitive format to show the relative degenerative painful chemical comparisons between discs to assist a doctor, in combination with other available patent data, in diagnosing disc conditions, such as discogenic pain and/or degenerative disc disease.

GOING BEYOND

Traditional Back Pain Diagnosis

Standard Regimens & Alternatives
Physical Examination e.g. for functional deficits and pain distribution profile.
Standard Imaging Techniques e.g. MRI, X-ray, myelogram.
Selective Nerve Blocks Needles are injected into a spinal nerve, sacroiliac joint, facet or medial joints.
Provocative Discography Patient provides a pain level after a needle is inserted into a lumbar disc & pressurized.

GOING BEYOND

Traditional Back Pain Diagnosis

Standard Regimens & Alternatives
Physical Examination e.g. for functional deficits and pain distribution profile.
Standard Imaging Techniques e.g. MRI, X-ray, myelogram.
Selective Nerve Blocks Needles are injected into a spinal nerve, sacroiliac joint, facet or medial joints.
Provocative Discography Patient provides a pain level after a needle is inserted into a lumbar disc & pressurized.

A BETTER WAY

NOCISCAN-LS™ Lumbar Spectroscopy Exam

A Revolutionary Tool Used to Help Diagnose Lumbar Back Pain

NOCISCAN Suite results are correlated with the results of a more invasive and painful discography reference test for identifying painful discs. NOCISCAN Suite clinical trial results also show improved outcomes for patients who received treatment at the discs identified with the highest relative scores for degenerative painful disc chemicals.

Nocimed harnesses the existing power of Magnetic Resonance Spectroscopy (MRS), a derivative of Magnetic Resonance Imaging (MRI), for non-invasive, objective quantification of relative chemical differences in tissues – but specifically applied to assess the relative chemical biomarkers for tissue degeneration and pain in lumbar discs.

OUR SOFTWARE

NOCISCAN™ Suite

NOCISCAN™ Suite is a software suite that works with existing high field MR systems and MRS pulse sequence packages via an optimized protocol to conduct MRS exams of lumbar discs. The software suite post-processes the NOCISCAN-LS disc MRS exam data to calculate ratios of spectroscopic signals at regions along the MRS frequency spectrum associated with certain chemicals that change with degeneration and pain.

TWO PRIMARY MODULES

NOCISCAN-LS Disc MRS Exam Protocol

A set of custom settings and parameters for using an existing, customizable MRS pulse sequence that is commercially available by the MR scanner manufacturer as an option or upgrade installation to standard high field MRI systems with MRS capabilities.

This NOCISCAN-LS Exam protocol instructs the MR system to run the uniquely directed MRS examination of the lumbar discs. Reach out to Nocimed for a list of compatible scanners.

NOCISCAN-LS Disc MRS Post-Processor

A cloud-based software engine that receives the information acquired during the NOCISCAN-LS exam and processes that information through various algorithms to provide optimally robust MRS spectra, spectral measurements, and calculated chemical assessment results. This includes the NOCICALC-LS and NOCIGRAM-LS post-processing products.

The NOCISCAN-LS disc MRS Post-Processor is hosted in a secured and protected environment via a leading commercial cloud-host vendor, with data transport connectivity via a secured internet gateway with a picture archiving and communications system (PACS) network associated with the MR scanner.

Reach out to Nocimed for examples of NOCICALC-LS and NOCIGRAM-LS Reports.

Contact us for more information or schedule a demo.